An exciting time for genome editing: an interview with David R. Liu     

Weijie Zhao  Kevin T Zhao 《国家科学评论(英文版)》2019,6(3):452

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Nonlinear growth curves in developmental research     

Grimm KJ  Ram N  Hamagami F 《Child development》2011,82(5):1357-1371

Developmentalists are often interested in understanding change processes, and growth models are the most common analytic tool for examining such processes. Nonlinear growth curves are especially valuable to developmentalists because the defining characteristics of the growth process such as initial levels, rates of change during growth spurts, and asymptotic levels can be estimated. A variety of growth models are described beginning with the linear growth model and moving to nonlinear models of varying complexity. A detailed discussion of nonlinear models is provided, highlighting the added insights into complex developmental processes associated with their use. A collection of growth models are fit to repeated measures of height from participants of the Berkeley Growth and Guidance Studies from early childhood through adulthood.  相似文献   

Engaging Undergraduates in Science Research: Not Just About Faculty Willingness     

Eagan MK  Sharkness J  Hurtado S  Mosqueda CM  Chang MJ 《Research in higher education》2011,52(2):151-177

Despite the many benefits of involving undergraduates in research and the growing number of undergraduate research programs, few scholars have investigated the factors that affect faculty members’ decisions to involve undergraduates in their research projects. We investigated the individual factors and institutional contexts that predict faculty members’ likelihood of engaging undergraduates in their research project(s). Using data from the Higher Education Research Institute’s 2007–2008 Faculty Survey, we employ hierarchical generalized linear modeling to analyze data from 4,832 science, technology, engineering, and mathematics (STEM) faculty across 194 institutions to examine how organizational citizenship behavior theory and social exchange theory relate to mentoring students in research. Key findings show that faculty who work in the life sciences and those who receive government funding for their research are more likely to involve undergraduates in their research project(s). In addition, faculty at liberal arts or historically Black colleges are significantly more likely to involve undergraduate students in research. Implications for advancing undergraduate research opportunities are discussed.  相似文献   

Attitudes to cadaveric organ donation in Irish preclinical medical students     

Cahill KC  Ettarh RR 《Anatomical sciences education》2011,4(4):195-199

There is a worldwide shortage of organs for transplantation. It has been shown that the attitude of healthcare professionals can improve the rates of organ donation, and that educational programs aimed at improving both attitudes and knowledge base of professionals can have positive outcomes. Although there has been research carried out on this topic, there has been none in Ireland. Anatomy dissection can be a stressor to medical students-we investigate the attitudes of Irish students to organ donation and how they change with exposure to anatomy dissection. A questionnaire was administered to first year students in the School of Medicine in University College Dublin, Ireland, three times over a nine-week period at the commencement of classes in an academic year. The attitudes of the students were positive throughout regarding organ donation by a stranger, a family member, or themselves. There was, however, a significant decrease in support for the donation of a family member's organs in a minority of students. Irish students' attitudes to postmortem organ donation are positive and are not changed by exposure to the dissecting room. There is support for the donation of organs, and willingness among students to donate their own organs and support donation by family members.  相似文献   

Harnessing technology to improve formative assessment of student conceptions in STEM: forging a national network   总被引：2，自引：0，他引：2  

Haudek KC  Kaplan JJ  Knight J  Long T  Merrill J  Munn A  Nehm R  Smith M  Urban-Lurain M 《CBE life sciences education》2011,10(2):149-155

Concept inventories, consisting of multiple-choice questions designed around common student misconceptions, are designed to reveal student thinking. However, students often have complex, heterogeneous ideas about scientific concepts. Constructed-response assessments, in which students must create their own answer, may better reveal students' thinking, but are time- and resource-intensive to evaluate. This report describes the initial meeting of a National Science Foundation-funded cross-institutional collaboration of interdisciplinary science, technology, engineering, and mathematics (STEM) education researchers interested in exploring the use of automated text analysis to evaluate constructed-response assessments. Participants at the meeting shared existing work on lexical analysis and concept inventories, participated in technology demonstrations and workshops, and discussed research goals. We are seeking interested collaborators to join our research community.  相似文献   

An analysis of the relationship between the linear hammer speed and the thrower applied forces during the hammer throw for male and female throwers     

Brice SM  Ness KF  Rosemond D 《Sports biomechanics / International Society of Biomechanics in Sports》2011,10(3):174-184

The purpose of this study was to investigate the relationship between the cable force and linear hammer speed in the hammer throw and to identify how the magnitude and direction of the cable force affects the fluctuations in linear hammer speed. Five male (height: 1.88 +/- 0.06 m; body mass: 106.23 +/- 4.83 kg) and five female (height: 1.69 +/- 0.05 m; body mass: 101.60 +/- 20.92 kg) throwers participated and were required to perform 10 throws each. The hammer's linear velocity and the cable force and its tangential component were calculated via hammer head positional data. As expected, a strong correlation was observed between decreases in the linear hammer speed and decreases in the cable force (normalised for hammer weight). A strong correlation was also found to exist between the angle by which the cable force lags the radius of rotation at its maximum (when tangential force is at its most negative) and the size of the decreases in hammer speed. These findings indicate that the most effective way to minimise the effect of the negative tangential force is to reduce the size of the lag angle.  相似文献   

Bowling ball dynamics revealed by miniature wireless MEMS inertial measurement unit   总被引：1，自引：1，他引：0  

Kevin King  N. C. Perkins  Hugh Churchill  Ryan McGinnis  Ryan Doss  Ron Hickland 《Sports Engineering》2011,13(2):95-104

This paper presents a novel sensor technology to deduce the dynamics of a bowling ball. The sensor, a miniature wireless inertial measurement unit (IMU), incorporates MEMS accelerometers and angular rate gyros, a microcontroller, a low power RF transceiver, and a rechargeable battery. When embedded in a bowling ball, the IMU transmits the acceleration and angular velocity data that define the dynamics of the ball starting with the bowler’s delivery and its motion in the lane. Example results from professional bowlers illustrate how this technology can be used to assess bowler skill and ball performance. For instance, the IMU accurately measures the spin dynamics of the ball which are crucial to develop the ball “hook.” An analysis of ball dynamics in the lane is distilled to a measurable “hook potential” metric for further assessing bowler skill. Finally, the sensor presented herein is believed to be the world’s smallest, wireless IMU. This highly miniaturized and wireless design will enable parallel training systems for many sports, including basketball, baseball, crew, cricket, golf, fly fishing, soccer, softball, tennis, rowing, among others.  相似文献   

Golf styles and centre of pressure patterns when using different golf clubs     

Ball KA  Best R 《Journal of sports sciences》2011,29(6):587-590

When using a driver, the centre of pressure of a golfer shows a pattern that is characteristic of one of two distinct swing styles: the "front foot" style or the "reverse" style. The aim of this study was to establish whether these two swing styles are also evident when using other clubs, and if so, to determine whether golfers use the same swing style when using different clubs. Forty-six professional, amateur, and recreational golfers performed swings to hit a ball into a net placed 3 m away. Ten swings were performed for each of the driver, 3-iron, and 7-iron while standing on two force plates. The position of the golfer's centre of pressure parallel with the line of shot and relative to the feet was quantified at eight swing events that were identified from 200-Hz video. Cluster analysis confirmed that the front foot and reverse styles were evident in all three clubs, and most of the golfers (96%) used the same swing style for all three clubs. Golfers that used the reverse swing positioned their centre of pressure nearer to their toes at ball contact compared with golfers that used the front foot swing.  相似文献   

The long-term athlete development model: physiological evidence and application   总被引：2，自引：2，他引：0  

Ford P  De Ste Croix M  Lloyd R  Meyers R  Moosavi M  Oliver J  Till K  Williams C 《Journal of sports sciences》2011,29(4):389-402

Within the UK, the "Long Term Athlete Development" (LTAD) model has been proposed by a variety of national governing bodies to offer a first step to considering the approach to talent development. The model, which is primarily a physiological perspective, presents an advancement of understanding of developing athletic potential alongside biological growth. It focuses on training to optimize performance longitudinally, and considers sensitive developmental periods known as "windows of opportunity". However, it appears that there are a number of problems with this theoretical model that are not necessarily transparent to coaches. Principally, the model is only one-dimensional, there is a lack of empirical evidence upon which the model is based, and interpretations of the model are restricted because the data on which it is based rely on questionable assumptions and erroneous methodologies. Fundamentally, this is a generic model rather than an individualized plan for athletes. It is crucial that the LTAD model is seen as a "work in progress" and the challenge, particularly for paediatric exercise scientists, is to question, test, and revise the model. It is unlikely that this can be accomplished using classical experimental research methodology but this should not deter practitioners from acquiring valid and reliable evidence.  相似文献   

Successful Concurrent Programs: An EXCELerate Program in Oklahoma     

Juanita Gamez Vargas  Rick Roach  Kevin M. David 《Community College Journal of Research & Practice》2014,38(2-3):166-173

The article presents the implementation and findings of a successful collaborative effort with the Oklahoma State Regents for Higher Education (OSRHE), Tulsa Community College (TCC), and two local public school districts, Tulsa Public Schools (TPS) and Union Public Schools (UPS). Known as EXCELerate, it's a five-semester dual enrollment pilot program that received state policy exceptions for juniors and seniors to enroll in dual enrollment courses and supportive resources from the participating agencies. Whereas the traditional dual enrollment student is White and college-going, the program's intent was to increase the number of high school students who may be first-generation, lower-socioeconomic, ethnic or non-ethnic. The article identifies three major barriers to successful dual enrollment and completion: state policy, financial issues, and transportation. It also examines how these barriers were eliminated through a collaborative effort. The results demonstrate that over 87% of the juniors and seniors persisted over the semesters, and enrollment tripled among African American and Latino students. The article is constructed to benefit further research and practical application for urban and rural community colleges.  相似文献